Acks

2 clues
Certain responses: Abbr.
Comic cries of frustration
Similar answers:
40winks
Aaacell
Aac
Aacell
Aacells
Aachen
Aacid
Aardvarks
Aaronburrconspiracy
Aarpvpoksbyob
Aattheraces
Abac
Abaca
Abacab
Abacas
Abaci
Aback
Abackseat
Abackwardpoet
Abaco