Nastiest

3 clues
Most spiteful
Most malicious
Most unpleasant
Similar answers:
Achiest
Adlaiestevenson
Aeriest
Afternoonsiesta
Airiest
Alamofiesta
Americanbdnastdna
Anastasia
Anastasiasteele
Anastasio
Anastrophe
Angriest
Annasten
Antsiest
Anyporkinastorm
Anyporterinastorm
Anyportinastorm
Anytorteinastorm
Apriest
Apriestarabbiandamonk