| Mr. Eban |
| All-star cast problems |
| Mr. Arnaz |
| Mr. Mojo ___ (anagrammatic nickname for Jim Morrison) |
| Lane who provided Mr. Ed's voice |
| Pilot's problem |
| Cause of stomach problems, sometimes |
| Mr. Bones, e.g. |
| A sickening amount of Mr. Bradley? |
| Tummy problem |
| Like Mr. America contenders |
| Inflamed eye problem |
| Tooth or tummy problem |
| Mr. Strauss |
| Hilarious joke or, with an acquired taste, "What's Mr. Pacino up to these days, Mr. Perry? |
| Am I the problem? |
| Angelina's "Mr. & Mrs. Smith" co-star |
| Bureaucratic problem |
| Mr. Tambourine Man" band at spelling competitions? |
| Mr. ___" (2002 remake) |
| Handle problems |
| George nicknamed "Mr. Basketball |
| Anonymous disclosure, and a problem at the end of each starred answer |
| Mrs. Malaprop's problem |
| She's a problem that needs to be solved, in song |
| Mr. Bumble's position in "Oliver Twist |
| Printing problems |
| Jet ___ (problem when changing time zones) |
| Mr. Motto's vocalist? |
| Baseball's Mr. Hustle |