| Actor Jared who fronts the band 30 Seconds to Mars |
| Actor who cross-dressed for his role in "Mrs. Doubtfire": 2 wds. |
| Czech Republic's second largest city |
| Exactly 10 seconds, for the 100-yard dash |
| Mrs. Bunker |
| Angelina's "Mr. & Mrs. Smith" co-star |
| Adam's first wife? — Frasier Crane's second ex-wife |
| Mrs. Malaprop's problem |
| Singer whose second album, "Unorthodox Jukebox," came out in December 2012: 2 wds. |
| Mrs. Jerry Stiller |
| Actress who played Mrs. Cunningham on "Happy Days |
| A Mrs. Mickey Rooney |
| Dairy farmer's wife who was named after Mrs. Julius Caesar? |
| A tragedy when seen in close-up, but a comedy in long-shot," according to Charlie Chaplin |
| Mrs. Colin Powell |
| Test releases of software, named for the second letter of the Greek alphabet |
| Mrs. Stengel |
| One-time Mrs. Sinatra |
| One in a second childhood |
| Second word of a Brian Hyland song title |
| Second application |
| Actress Wilson of "Mrs. Doubtfire |
| Mrs. Murphy's creations |
| Makes a second appraisal |
| Finished second |
| Act like Mrs. Mitty |
| Naval equivalent of second lieutenant |
| Second dinner course at the prison? |
| China's second imperial dynasty |
| Mrs. Oskar Schindler |