| Kermit making a significant change? |
| Achieve significant progress |
| Insignificant spread? |
| Insignificant person, metaphorically |
| Significant stretches of time |
| Insignificant speck |
| Insignificantly |
| Insignificantly small |
| Superlatively insignificant |
| Ships' drop-off locale? |
| Insignificant guy (and #7 on the "Top Ten Words That Sound Romantic When Spoken By Barry White") |
| Penny-__ (insignificant) |
| Insignificant woodpile? |
| Insignificant haunches |
| Insignificant upturn |
| Insignificant, as chatter |
| Insignificant recovery after a steep market drop |
| Insignificant duel partner? |
| Insignificant deLillos album? |
| Significant chunks of time |
| Remote and insignificant |
| Insignificant thing |
| Insignificant recovery in a stock price |
| Insignificant amount |
| Newly-introduced element that alters the situation in a significant way, in modern lingo |
| Insignificant one |
| Most significant entitlement |
| Insignificant specks |
| Insignificant New York band? |
| Insignificant disruption |