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She played Lois opposite Christopher's Clark
She played Lola
She played Lucinda in "Oscar and Lucinda
She played Maerose in "Prizzi's Honor
She played Maggie in "Pete Kelly's Blues" (1955)
She played Malcolm-Jamal Warner's sister
She played Mame
She played Margo in "All About Eve
She played Maria Callas in 'Master Class'
She played Marilyn Miller
She played Marion in "Psycho
She played Mary Hartman
She played Master Viper in "Kung Fu Panda
She played Maude
She played Maude Findlay
She played Maude on "Maude
She played Megan in "Funky Monkey
She played Michelle on "Full House
She played Miss Brooks
She played Molly in ''Ghost''
She played Mother Superior in "Sister Act": 2 wds.
She played Mrs. Charles
She played Mrs. Garrett
She played Mrs. Garrett on both "Diff'rent Strokes" and "The Facts of Life
She played Mrs. Miniver in "Mrs. Miniver
She played Mrs. Ted Baxter
She played Musette to Gish's Mimi in "La Boheme," 1926
She played Nana in "Nana
She played Natasha in 2000's "The Adventures of Rocky and Bullwinkle
She played Natasha in "The Adventures of Rocky and Bullwinkle
She played Nell in "Nell
She played Nicole Chapman on "Fame
She played Niles's wife on "Frasier
She played Ninotchka
She played Nora Charles
She played Nora in "The Thin Man
She played Nora to William's Nick
She played Odin's wife in "Thor
She played Olive Madison opposite Struthers's Florence Ungar in a 1985 Broadway version of "The Odd Couple
She played one of Charlie's Angels
She played one of the Bundys
She played one of the "Golden Girls
She played O'Shaughnessy opposite Bogart's Spade
She played Pam on "The Office
She played Pandora in "Pandora and the Flying Dutchman
She played Phyllis on TV
She played Phyllis on TV's "Phyllis
She played Principal McGee in "Grease
She played Professor McGonagall
She played Rebecca in the 1952 "Ivanhoe
She played Rhoda Morgenstern in a "Mary Tyler Moore Show" spin-off: 2 wds.
She played Rita in "Groundhog Day
She played Romy in "Romy and Michele's High School Reunion
She played Rory in "Gilmore Girls
She played Rose Nylund on "The Golden Girls
She played Rose Sayer in a classic 1951 film, casually
She played Rosemary
She played Rosemary in "Rosemary's Baby
She played Roxie in "Chicago
She played Roxie on-screen
She played Roxy on "Dead Like Me
She played Rudy on "The Cosby Show
She played Sabrina Duncan on the original "Charlie's Angels" TV series: 2 wds.
She played Sally in "When Harry Met Sally ...
She played Samantha on "Who's the Boss?
She played Sarah Connor in "Terminator 2: Judgment Day": 2 wds.
She played Sarah in "The Bible
She played Sasha Monroe on "Third Watch
She played Scarlett
She played Sean Penn's girlfriend in her film debut
She played Sephora to Heston's Moses
She played Serena on "Gossip Girl": 2 wds.
She played "She
She played Shirley on "Laverne & Shirley": 2 wds.
She played Shirley's daughter in "Terms of Endearment
She played Sidney in "Scream
She played singer Lili von Shtupp in "Blazing Saddles": 2 wds.
She played Sissy in "Urban Cowboy
She played Sister Aloysius Beauvier in "Doubt": 2 wds.
She played Sophie
She played Sophie in "Sophie's Choice
She played Spike Lee's girlfriend in "Do the Right Thing
She played Stella Johnson
She played Sue Ann Nivens on "The Mary Tyler Moore Show
She played Susan on "Suddenly Susan
She played the 10 in "10
She played the baker's wife in "Into the Woods
She played "the basket case" Allison in "The Breakfast Club": 2 wds.
She played the Black Swan in "Black Swan
She played the Bond girl in "Goldfinger
She played the created object of desire in "Weird Science
She played the devil in "Bedazzled
She played the House Bunny in "The House Bunny
She played the mom on 'Good Times'
She played the Palace
She played the pretty woman in "Pretty Woman
She played "the princess" Claire in "The Breakfast Club": 2 wds.
She played the title role in the 1982 TV movie "Mae West
She played the title role in the sitcom "Alice
She played the witness for the prosecution in "Witness for the Prosecution
She played the woman in "A Man and a Woman
She played Thelma
She played Thelma in "Thelma and Louise
She played Thelma in "Thelma & Louise
She played Tina
She played Tom Bosley's TV daughter
She played Truvy Jones in "Steel Magnolias
She played Tugboat Annie
She played TV's Amanda Woodward
She played TV's Maude
She played Ursula Andress in "The Life and Death of Peter Sellers
She played Virginia in "The Hours
She played Wallis Simpson in "The King's Speech
She played W.C.'S "chickadee
She played WKRP's Jennifer
She played Yentl
She plays an actress-turned-wrestler in the Netflix series "GLOW": 2 wds.
She plays Ana in 'Fifty Shades of Grey'
She plays Ana on TV's "Telenovela
She plays Archie Andrews's mother on "Riverdale
She plays Bree Hodge on "Desperate Housewives
She plays Brenda in "The Closer
She plays Carla on "Cheers
She plays Carmela
She plays Carmela on "The Sopranos
She plays Catherine on "CSI
She plays Cersei Lannister on "Game of Thrones
She plays Crawford in FX's "Feud
She plays Denise Huxtable on TV
She plays Dr. Amy Farrah Fowler—a neurobiologist—on CBS's "The Big Bang Theory": 2 wds.
She plays Dr. Meredith Grey—a surgeon—on ABC's "Grey's Anatomy": 2 wds.
She plays Dr. Temperance Brennan—a forensic anthropologist—on Fox's "Bones": 2 wds.
She plays Eleanor in "Stuart Little
She plays Galadriel in "The Hobbit: The Desolation of Smaug": 2 wds.
She plays Gamora in "Guardians of the Galaxy": 2 wds.
She plays Hannah on "Girls
She plays Harry's friend Hermione
She plays Hermione
She plays Hermione in "Harry Potter" films
She plays Hillary Altman in "This Is Where I Leave You": 2 wds.
She plays Jackie on "Nurse Jackie
She plays Jane in 'The Twilight Saga'
She plays Jane on "Jane The Virgin
She plays Jess on "New Girl": 2 wds.
She plays Jessica
She plays Jessica on TV
She plays Julia in "Julie & Julia
She plays Leslie on "Parks and Recreation
She plays Lila Quartermaine on "General Hospital